All-in-one dual-aptasensor capable of rapidly quantifying carcinoembryonic antigen

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• 作者：Harriet Khang¹ ; Kelly Cho¹ ; Stephanie Chong¹ ; Ji Hoon Lee ; ^{jhlee@luminescentmd.com}
• 关键词：Carcinoembryonic antigen (CEA) ; Dual aptamer ; G-quadruplex DNAzyme ; Dual-aptasensor ; Aptasensor ; 1 ; 1&prime ; -oxalyldiimidazole chemiluminescence (ODI-CL)
• 刊名：Biosensors and Bioelectronics
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：46-52
• 全文大小：578 K
• 卷排序：90

文摘

Design of dual DNA aptamers capable of rapidly capturing CEA and hemin. Competition of CEA and hemin to bind with the dual DNA aptamer in human serum. All-in-one dual-aptasemsor devised with the combination of CEA, hemin and dual DNA aptamer. Rapid quantification of CEA using the all-in-one dual-aptasensor with good reproducibility.