Method translation and full metadata transfer from thermal to differential flow modulated comprehensive two dimensional gas chromatography: Profiling of suspected fragrance allergens

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• 作者：Chiara Cordero^a ; ^{chiara.cordero@unito.it} ; Patrizia Rubiolo^a ; Stephen E. Reichenbach^b ; Andrea Carretta^c ; Luigi Cobelli^c ; Matthew Giardina^d ; Carlo Bicchi^a
• 关键词：Two-dimensional comprehensive gas chromatography&ndash ; mass spectrometry and flame ionization detection ; Reverse-inject differential flow modulation ; Quantitative profiling ; Suspected fragrance allergens ; Method translation ; Template matching functions
• 刊名：Journal of Chromatography A
• 出版年：2017
• 出版时间：13 January 2017
• 年：2017
• 卷：1480
• 期：Complete
• 页码：70-82
• 全文大小：3205 K
• 卷排序：1480

文摘

Simple operations driven by dedicated software enable effective method translation. Effective method translation between thermal and differential flow modulated GC × GC. 2D peak patterns misalignment evaluation and challenges for metadata transfer. Effective automated and supervised template matching for metadata alignment between patterns. Accurate quantitative screening/profiling of cosmetic allergens based on response factors.