Measurement and correlation of solubility of ciclesonide in seven pure organic solvents

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• 作者：Lina Zhou^a ; ^b ; Qiuxiang Yin^a ; ^b ; Zhiqiang Guo^c ; Haijiao Lu^a ; ^b ; Mingyan Liu^a ; ^b ; ^{myliu@tju.edu.cn} ; Wei Chen^a ; ^b ; Baohong Hou^a ; ^b
• 关键词：Ciclesonide ; Solubility ; Interaction force ; Thermodynamics
• 刊名：The Journal of Chemical Thermodynamics
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：105
• 期：Complete
• 页码：133-141
• 全文大小：762 K
• 卷排序：105

文摘

The solubility of ciclesonide in seven pure organic solvents was determined by gravimetric method. The solubility order was interpreted by virtue of density function theory (DFT). The experimental solubility of ciclesonide was correlated by four thermodynamic models. Mixing thermodynamic properties of ciclesonide were calculated and discussed.