One pot synthesis of unsymmetrical ketones from carboxylic and boronic acids via PyClU-mediated acylative Suzuki coupling

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• 作者：Pedro M. Garcia-Barrantes ; Kevin McGowan ; Steven W. Ingram ; Craig W. Lindsley ; ^{craig.lindsley@vanderbilt.edu}
• 关键词：PyClU ; Suzuki-Miyaura ; One pot ; Cross-coupling ; Boronic acid
• 刊名：Tetrahedron Letters
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：58
• 期：9
• 页码：898-901
• 全文大小：415 K
• 卷排序：58

文摘

One pot PyClU-mediated acylative Suzuki Coupling of unsymmetrical ketones. No additional phosphine ligands required. Reactions proceed at room temperature in under 2 h. >30 examples, up to 92% yield.