pH-dependent absorption spectra of rhodopsin mutant E113Q: On the role of counterions and protein

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• 作者：Peng Xie^a ; Panwang Zhou^a ; Ahmed Alsaedi^b ; Yan Zhang^a ; ^{zhangyanhg@dicp.ac.cn}
• 关键词：Spectra tuning ; QM/MM ; E113Q rhodopsin ; Hydrogen-bond ; Anion biosensor
• 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
• 出版年：2017
• 出版时间：5 March 2017
• 年：2017
• 卷：174
• 期：Complete
• 页码：25-31
• 全文大小：1180 K
• 卷排序：174

文摘

The absorption spectral tuning mechanism of E113Q rhodopsin in dark state at different pH values is elaborated. The counterions around Schiff base are more crucial than the protein environments to affect the absorption spectra of E113Q. E113Q rhodopsin has the potential for use as a template of anion biosensors at visible wavelength.