An in-source multiple collision-neutral loss filtering based nontargeted metabolomics approach for the comprehensive analysis of malonyl-ginsenosides from Panax ginseng, P. quinquefolius, and P. notoginseng

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• 作者：Xiao-jian Shi^a ; ^b ; ¹ ; Wen-zhi Yang^b ; ¹ ; Shi Qiu^b ; Chang-liang Yao^b ; Yao Shen^b ; Hui-qin Pan^b ; Qi-rui Bi^a ; ^b ; Min Yang^b ; Wan-ying Wu^b ; ^{wanyingwu@simm.ac.cn} ; De-an Guo^a ; ^b ; ^{daguo@simm.ac.cn}
• 关键词：In-source multiple collision-neutral loss filtering ; Improved nontargeted metabolomics ; Malonyl-ginsenoside ; Panax ; Chemical marker
• 刊名：Analytica Chimica Acta
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：952
• 期：Complete
• 页码：59-70
• 全文大小：2370 K
• 卷排序：952

文摘

An IMC-NLF-based nontargeted metabolomics approach was developed. It enables the characterization and statistical analysis of target components. Dual neutral loss filtering facilitates the exact screening of malonyl-ginsenosides. 101 malonyl-ginsenosides were primarily characterized from three Ginseng species. Ten potential markers were discovered for discriminating three Ginseng species.