iTRAQ-based quantitative proteomic analysis of midgut in silkworm infected with Bombyx mori cytoplasmic polyhedrosis virus

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• 作者：Kun Gao ; Xiang-yuan Deng ; Meng-ke Shang ; Guang-xing Qin ; Cheng-xiang Hou ; Xi-jie Guo ; ^{guoxijie@126.com}
• 关键词：Bombyx mori ; Cytoplasmic polyhedrosis virus ; iTRAQ ; Midgut ; Proteome
• 刊名：Journal of Proteomics
• 出版年：2017
• 出版时间：30 January 2017
• 年：2017
• 卷：152
• 期：Complete
• 页码：300-311
• 全文大小：1286 K
• 卷排序：152

文摘

Proteomes of the silkworm midgut after BmCPV infection investigated via iTRAQ. Total 193, 408, 189 DEPs larvae were detected at 24, 48, 72 hpi respectively. Some important DEPs and co-DEPs were verified using qRT-PCR. p62/sequestosome-1 protein was upregulated both at the proteomic and mRNA level. It was provided clues on the defense mechanisms of silkworm to BmCPV infection.