A proteomic approach to compare saliva from individuals with and without oral leukoplakia

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• 作者：Danielle Resende Camisasca^a ; ^{daniellecamisasca@yahoo.com.br} ; Lorena da R&oacute ; s Gonç ; alves^b ; ^{lorena.da@terra.com.br} ; Má ; rcia Regina Soares^c ; ^{marcia@iq.ufrj.br} ; Vanessa Sandim^b ; ⁱ ; ^{nessasandim@gmail.com} ; Fá ; bio Cé ; sar Sousa Nogueira^c ; ^{fabiocsn@gmail.com} ; ^{fabiocsn@ufrj.br} ; Carlos Henrique Saraiva Garcia^c ; ^{scarlogarcia@gmail.com} ; Rodrigo Santana^b ; ^{chokus05@hotmail.com} ; Silvia Paula de Oliveira^d ; ^{silviaoliv@hotmail.com} ; Luisa Aguirre Buexm^e ; ^{labuexm@hotmail.com} ; Paulo Antô ; nio Silvestre de Faria^f ; ^{pauloafaria@gmail.com} ; Fernando Luiz Dias^g ; ^{fdias@inca.gov.br} ; Denise de Abreu Pereira^b ; ^{deniseap@inca.gov.br} ; Russolina B. Zingali^h ; ⁱ ; ^{lzingali@bioqmed.ufrj.br} ; Gilda Alves^b ; ^{galvesbrown@gmail.com} ; Simone Queiroz Chaves Lourenç ; o^a ; ^{silourenco2015@gmail.com}
• 关键词：Keratin-10 ; MALDI-MS ; Oral leukoplakia ; Saliva ; 2D gel electrophoresis
• 刊名：Journal of Proteomics
• 出版年：2017
• 出版时间：16 January 2017
• 年：2017
• 卷：151
• 期：Complete
• 页码：43-52
• 全文大小：838 K
• 卷排序：151

文摘

2DE is suitable to identify differences in salivary proteins from OL and controls. Common proteins, such as alpha amylase, immunoglobulin and albumin were identified. Keratin 10, apolipoprotein A1, lysozyme precursor deserve further investigation. Keratin 10 was present in all tissues from two different set of patients. Areas with orthokeratin dysplasia were more prone to be CK10 positive.