A new megastigmane from fresh roots of Rehmannia glutinosa

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• 作者：Weisheng Feng ; Yanyan Lv ; Xiaoke Zheng ; Yanli Zhang ; Yangang Cao ; Yuanyuan Pei
• 关键词：Scrophulariaceae ; Rehmannia glutinosa ; Chemical constituents ; Iridoids
• 刊名：Acta Pharmaceutica Sinica B
• 出版年：2013
• 出版时间：September, 2013
• 年：2013
• 卷：3
• 期：5
• 页码：333-336
• 全文大小：419 K

文摘

A new megastigmane, rehmamegastigmane (1), together with eighteen known compounds lariciresinol (2), lariciresinol-4¡ä-O-¦Â-d-glucopyranoside (3), hierochin D (4), yemuoside YM1 (5), darendoside B (6), decaffeoylacteoside (7), jionoside B₁ (8), catalpol (9), ajugol (10), 6-O-vanilloylajugol (11), 6-O-E-feruloylajugol (12), rehmapicroside (13), rehmapicrogenin (14), 3-methoxy-2,6,6-trimethylcyclohexane-1-enecarboxylic acid (15), vanillic acid (16), hydroferulic acid (17), threo-1-(4-hydroxy-3-methoxyphenyl)-1,2,3-propanetriol (18), p-hydroxyphenylethyl alcohol (19) was isolated from the fresh roots of Rehmannia glutinosa. Compounds 2-6 and 16-18 were isolated from this plant for the first time.