Physiological responses and changes in gene expression in the large yellow croaker Larimichthys crocea following exposure to hypoxia

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• 作者：Qian-Feng Wang^a ; ^b ; Wei-Liang Shen^b ; Cong-Cong Hou^a ; Cheng Liu^a ; ^b ; Xiong-Fei Wu^b ; Jun-Quan Zhu^a ; ^{zhujunquan@nbu.edu.cn}
• 关键词：Larimichthys crocea ; Hypoxia ; Antioxidant system ; Hsp70 ; HIF-1α ; Histology
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：169
• 期：Complete
• 页码：418-427
• 全文大小：4255 K
• 卷排序：169

文摘

This page studied the effects of acute hypoxia on Larimichthys crocea in molecules and histology. The hemoglobin concentration, activities of antioxidant enzymes in liver (SOD and CAT) and biological indicators in serum (AST, ALT, AKP and CK-MB) all increased compared with control among hypoxia. The expression of Hsp70 and HIF-1α mRNA levels in the blood, liver, kidney and gills were significantly up-regulation among hypoxia. Paraffin sections showed that acute hypoxia could injure the liver, kidney and gills of L. crocea.