A novel method for assessing the toxicity of silver nanoparticles in Caenorhabditis elegans

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• 作者：Xun Luo^a ; ^b ; ^d ; Shengmin Xu^a ; ^c ; ^{shmxu@mail.ustc.edu.cn} ; Yaning Yang^a ; ^c ; Yajun Zhang^a ; ^c ; Shunchang Wang^d ; Shaopeng Chen^a ; ^c ; An Xu^a ; ^c ; Lijun Wu^a ; ^b ; ^c ; ^{ljw@ipp.ac.cn}
• 关键词：NGG ; AgNPs toxicity ; Germ cell apoptosis ; C. elegans ; Nanotoxicity
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：648-657
• 全文大小：2574 K
• 卷排序：168

文摘

A semi-fluid NGG method for assessing toxicity of AgNPs using C. elegans is proposed. AgNPs affect germ cell apoptosis, reproductive ability and lifespan of C. elegans. The semi-fluid NGG has more advantages and sensitivity for evaluating the toxicity of AgNPs using C. elegans. For semi-fluid NGG, the population growth assay is firstly applied to detect ecological toxicity of AgNPs.