Cadmium exposure is associated with soluble urokinase plasminogen activator receptor, a circulating marker of inflammation and future cardiovascular disease

详细信息    查看全文

• 作者：Bj&ouml ; rn Fagerberg^a ; ¹ ; ^{bjorn.fagerberg@wlab.gu.se} ; Yan Borné ; ^b ; ¹ ; Lars Barregard^c ; Gerd Sallsten^c ; Niklas Forsgard^d ; Bo Hedblad^b ; Margaretha Persson^b ; Gunnar Engstr&ouml ; m^b
• 关键词：ANOVA ; analysis of variance ; BMI ; body mass index ; CRP ; C-reactive protein ; HDL ; high density lipoprotein ; IQR ; interquartile range ; LDL ; low density lipoprotein ; Lp-PLA2 ; Lipoprotein-associated phospholipase A2 ; MDCS ; Malm&ouml ; Diet and Cancer Study ; NHANES ; National Health and Nutrition Examination Survey ; SD ; standard deviation ; suPAR ; soluble urokinase-type plasminogen activator receptor ; uPAR ; urokinase-type plasminogen activator receptor ; WBC ; white blood cell count
• 刊名：Environmental Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：152
• 期：Complete
• 页码：185-191
• 全文大小：270 K
• 卷排序：152

文摘

Cadmium is a toxic proinflammatory, proatherosclerotic metal. Soluble urokinase-type plasminogen activator receptor (suPAR) in plasma is a promising proinflammatory marker of atherosclerosis. Blood cadmium and plasma suPAR were measured in a cohort of 4648 Swedish men and women. Blood cadmium was positively associated with plasma suPAR, also in never smokers.