Glutathione and zebrafish: Old assays to address a current issue

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• 作者：Andrey Massarsky ; ^{andrey.massarsky@duke.edu} ; Jordan S. Kozal ; Richard T. Di Giulio
• 关键词：Zebrafish ; Oxidative stress ; Glutathione (GSH ; GSSG) ; Glutathione peroxidase (GPx) ; Glutathione reductase (GR)
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：707-715
• 全文大小：839 K
• 卷排序：168

文摘

Several xenobiotic agents induces reactive oxygen species (ROS). Zebrafish is a common model for the study of xenobiotic toxicity. Glutathione a main antioxidant that neutralizes ROS. Glutathione peroxidase (GPx) and reductase (GR) are important antioxidant enzymes. Simple methods to measure glutathione, and activities of GPx and GR are outlined.