A highly selective two-photon fluorogenic probe for formaldehyde and its bioimaging application in cells and zebrafish

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• 作者：Zhenda Xie^a ; ¹Author Vitae ; Jingyan Ge^a ; ¹Author Vitae ; Huatang Zhang^bAuthor Vitae ; Tianwen Bai^cAuthor Vitae ; Siyang He^aAuthor Vitae ; Jun Ling^cAuthor Vitae ; Hongyan Sun^d ; ^{hongysun@cityu.edu.hk}Author Vitae ; Qing Zhu^a ; ^{zhuq@zjut.edu.cn}Author Vitae
• 关键词：Intramolecular charge transfer ; Formaldehyde ; TD-DFT ; Zebrafish bioimaging ; Fluorescent probe
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：31 March 2017
• 年：2017
• 卷：241
• 期：Complete
• 页码：1050-1056
• 全文大小：1599 K
• 卷排序：241

文摘

A high selective and two-photon fluorogenic probe (TPNF) for detecting formaldehyde was developed. A time-dependent density functional theory calculation was performed to demonstrate the turn on mechanism of the probe. HeLa cells and zebrafish larvae imaging experiments reveal that TPNF is a promising tool in the further biomedical research.