Label-free and sensitive sialic acid biosensor based on organic electrochemical transistors

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• 作者：Xiang Guo^aAuthor Vitae ; Jing Liu^aAuthor Vitae ; Feiyan Liu^aAuthor Vitae ; Fang She^aAuthor Vitae ; Qiong Zheng^aAuthor Vitae ; Hao Tang^a ; ^{tanghao@hunnu.edu.cn}Author Vitae ; Ming Ma^aAuthor Vitae ; Shouzhuo Yao^a ; ^bAuthor Vitae
• 关键词：Organic electrochemical transistors ; Label-free ; Poly-3-aminophenylboronic acid ; Sialic acid ; Biosensing
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：1075-1082
• 全文大小：1630 K
• 卷排序：240

文摘

Disposable organic electrochemical transistors (OECTs) were prepared using screen-printed electrodes on flexible substrates. Poly (3-aminophenylboronic acid)-modified electrode served as the gate electrode. The OECT device exhibits good analytical performances for label-free detection of sialic acid. The device has the capacity to identify cancer and normal cells in a simple and noninvasive way.