Near-infrared electrochemiluminesence biosensor for high sensitive detection of porcine reproductive and respiratory syndrome virus based on cyclodextrin-grafted porous Au/PtAu nanotube

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• 作者：Kang Shao¹Author Vitae ; Chenjun Zhang¹Author Vitae ; Shiyi YeAuthor Vitae ; Kai CaiAuthor Vitae ; Long WuAuthor Vitae ; Biru WangAuthor Vitae ; Chenchen ZouAuthor Vitae ; Zhicheng LuAuthor Vitae ; Heyou Han ; ^{hyhan@mail.hzau.edu.cn}Author Vitae
• 关键词：Porcine reproductive and respiratory syndrome virus ; Near&ndash ; infrared ; Electrochemiluminescence ; PtAu nanotube ; Enzyme catalysis
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：586-594
• 全文大小：3219 K
• 卷排序：240

文摘

We firstly prepared porous PtAu bimetallic heterojunction nanotubes-cyclodextrin nano-composites for synergetic signal amplification. Developing a near–infrared electrochemiluminesence immunosensor for porcine reproductive and respiratory syndrome virus. The sensitive detection limit (∼10.8 pg/mL) was increased by two orders of magnitude than fluorometry. 5.1-fold signal enhancement caused by porous PtAu bimetallic heterojunction nanotubes and cyclodextrin-adamantane.