Magnitude of viremia, antigenemia and infection of circulating monocytes in children with mild and severe dengue

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• 作者：Federico Perdomo-Celis^a ; Doris M. Salgado^a ; ^b ; Carlos F. Narvá ; ez^a ; ^{cfnarvaez@usco.edu.co}
• 关键词：Dengue ; Viremia ; NS1 ; Monocytes ; Pediatric
• 刊名：Acta Tropica
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：167
• 期：Complete
• 页码：1-8
• 全文大小：1243 K
• 卷排序：167

文摘

Early viremia and antigenemia were found in children with DENV infection. The monocytes were the primary targets of DENV within blood mononuclear cells. Viremia and antigenemia were higher in primary infections than in secondary infections. The virological parameters were not associated with clinical severity. The levels of NS1 and DENV-infected monocytes were associated with coagulation disorders.