A mild and efficient method for bromination of alcohols using 伪,伪-dibromo-尾-dicarbonyl compounds as halogen sources

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• 作者：Xiao-Meng Cui ; Yong-Hong Guan ; Na Li ; Hao Lv ; Lin-An Fu ; Kun Guo ; Xiaohui Fan
• 关键词：Appel reaction ; 伪 ; 伪-Dibromo-尾-dicarbonyl compound ; Alcohol to bromide ; Triphenylphosphine
• 刊名：Tetrahedron Letters
• 出版年：1 January, 2014
• 年：2014
• 卷：55
• 期：1
• 页码：90-93
• 全文大小：2636 K

文摘

Exploration of 伪,伪-dibromo-尾-dicarbonyl compounds as novel bromine agents for the conversion of alcohols to alkyl bromides under neutral conditions has been achieved. This method can be used for acid-sensitive substrates and allows the bromination of various primary and secondary alcohols to proceed at room temperature within a very short period of time.