Genetic variants of the MAVS, MITA and MFN2 genes are not associated with leprosy in Han Chinese from Southwest China

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• 作者：Dong Wang^a ; Guo-Dong Li^a ; ^e ; Deng-Feng Zhang^a ; Ling Xu^a ; Xiao-An Li^b ; Xiu-Feng Yu^c ; Heng Long^c ; Yu-Ye Li^d ; Yong-Gang Yao^a ; ^e ; ^{yaoyg@mail.kiz.ac.cn}
• 关键词：Leprosy ; MAVS ; MITA ; MFN2 ; SNP ; Susceptibility
• 刊名：Infection, Genetics and Evolution
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：45
• 期：Complete
• 页码：105-110
• 全文大小：893 K
• 卷排序：45

文摘

We analyzed 11 SNPs of MAVS, MITA and MFN2 in Chinese with or without leprosy. Genotype, allele and haplotype frequencies were compared between cases and controls. Lack of association between SNPs of MAVS, MITA and MFN2 and leprosy No enrichment of potentially damaging variants of MAVS, MITA and MFN2 in leprosy