No increase of local recurrence rate in breast cancer patients treated with skin-sparing mastectomy followed by immediate breast reconstruction

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• 作者：D.R.J. van Mierlo ; T.R. Lopez Penha ; R.J. Schipper ; M.H. Martens ; J. Serroyen ; M.B.I. Lobbes ; E.M. Heuts ; S. Tuinder ; M.L. Smidt
• 关键词：Breast cancer ; Reconstructive surgical procedure ; Local neoplasm recurrence ; Post-operative complications
• 刊名：The Breast
• 出版年：December, 2013
• 年：2013
• 卷：22
• 期：6
• 页码：1166-1170
• 全文大小：213 K

文摘

Background

The aim of this study was to evaluate the incidence of local recurrence after SSM with IBR and to determine whether complications lead to postponement of adjuvant therapy.

Method

Patients that underwent IBR after SSM between 2004 and 2011 were included.

Results

A total of 157 reconstruction procedures were performed in 147 patients for invasive breast cancer (n聽=聽117) and ductal carcinoma in situ (n聽=聽40). The median follow-up was 39 months [range 6-97]. Estimated 5-year local recurrence rate was 2.9% (95%CI 0.1-5.7). The median time to start adjuvant therapy was 27.5 days [range 19-92] in 18 patients with complications, and 23.5 days [range 8-54] in 46 patients without complications (p聽=聽0.025).

Conclusion

In our single-institution cohort, IBR after SSM carried an acceptable local recurrence rate. Complications caused a delay of adjuvant treatment but this was within guidelines and therefore not clinically relevant.