Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation

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• 作者：Suresh Allamsetty^a ; ^c ; ¹ ; Li-Wei Lo^a ; ^b ; ¹ ; Yenn-Jiang Lin^a ; ^b ; Shih-Lin Chang^a ; ^b ; Fa-Po Chung^a ; ^b ; Yu-Feng Hu^a ; ^b ; Chin-Yu Lin^a ; Yao-Ting Chang^a ; ^b ; Cheng-Hung Chiang^a ; Hung-Kai Huang^a ; Chao-Shun Chan^a ; Van Bun Dan Do^a ; Chung-Hsing Lin^a ; Sunu Raharjo^a ; Shih-Jee Jhuo^a ; Rohit Walia^a ; Shih-Ann Chen^a ; ^b ; ^{epsachen@ms41.hinet.net}
• 关键词：Aorta ; Atrial fibrillation ; Encroachment ; Left atrium ; Trigger
• 刊名：International Journal of Cardiology
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：227
• 期：Complete
• 页码：650-655
• 全文大小：959 K
• 卷排序：227

文摘

Aortic dilatation was frequently observed in patients with atrial fibrillation (AF) and non-pulmonary vein (PV) triggers are important for mapping and ablation of AF. We hypothesized that the aortic encroachment area over left atrium (LA) could contribute to the local substrate characteristics.MethodsWe studied 32 consecutive patients of AF (age = 57.34 ± 8.07, male = 30), including 26 paroxysmal and 6 persistent AFs. Anatomic relationship between LA and aorta, and electrophysiological characteristics of the encroachment areas were investigated. IRB approval was taken.ResultsThe LA bipolar voltage (mean 0.49 ± 0.26 mV) was lower at aortic encroached area compared to global LA (mean 1.52 ± 0.48 mV) and it was statistically significant (p < 0.001). There was a linear correlation between the voltages of LA and distance from the aorta to the aortic encroachment area of LA (p < 0.001, R = 0.616). Non-PV triggers were observed in 34.37% (n = 11) of total patients. The initiation of AF in aortic encroached area was seen in 45.45% (n = 5) of non-PV trigger and 15.62% of total patients. All the patients were followed up for 6 months and 4 (14.81%) out of 27 patients without trigger at aortic encroached site of LA and 1 (20%) out of 5 patients with trigger at aortic encroached site of LA had recurrence of AF.ConclusionThe aorta contributed to low voltages on its encroachment area over the anterior wall of LA. Non-pulmonary vein triggers originating from the aortic encroachment area were found in 15.62% of total patients. Careful evaluation of the anatomical relationship between LA and aorta is important during AF ablation for a better long term outcome.