New Perspectives on Dry Eye Definition and Diagnosis: A Consensus Report by the Asia Dry Eye Society

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• 作者：Kazuo Tsubota ; MD ; PhD¹ ; ^{tsubota@z3.keio.jp} ; Norihiko Yokoi ; MD ; PhD² ; Jun Shimazaki ; MD ; PhD³ ; Hitoshi Watanabe ; MD ; PhD⁴ ; Murat Dogru ; MD ; PhD¹ ; ³ ; Masakazu Yamada ; MD ; PhD⁵ ; Shigeru Kinoshita ; MD ; PhD² ; Hyo-Myung Kim ; MD ; PhD⁶ ; Hung-Won Tchah ; MD ; PhD⁷ ; Joon Young Hyon ; MD ; PhD⁸ ; Kyung-Chul Yoon ; MD ; PhD⁹ ; Kyoung Yul Seo ; MD ; PhD¹⁰ ; Xuguang Sun ; MD ; PhD¹¹ ; Wei Chen ; MD ; PhD¹² ; Lingyi Liang ; MD ; PhD¹³ ; Mingwu Li ; MD ; PhD¹⁴ ; Zuguo Liu ; MD ; PhD¹⁵ ; Founding members of the Asia Dry Eye SocietyZuguo Liu ; Xuguang Sun ; Wei Chen ; Yingping Deng ; Jing Hong ; Ying Jie ; Mingwu Li ; Ying Li ; Lingyi Liang ; Hong Qi ; Hua Wang ; Xiaoming Yan ; Wenzhao Yang ; Yufeng Ye ; Jin Yuan ; Hong Zhang ; Hui Zhan ; Mingchang Zhang ; Shaozhen Zhao ; Hyo-Myung Kim ; Hungwon Tchah ; Chul Young Choi ; Eui-Sang Chung ; Joon Young Hyon ; Hyun-Seung Kim ; Mee Kum Kim ; Myoung-Joon ; Tae-Im Kim ; Do-Hyung Lee ; Hyung-Keun Lee ; Kyoung Yul Seo ; Jong Suk Song ; Kyung-Chul Yoon ; Kazuo Tsubota ; Norihiko Yokoi ; Shiro Amano ; Reiko Arita ; Murat Dogru ; Yuichi Hori ; Tetsuya Kawakita ; Motoko Kawashima ; Shizuka Koh ; Kohji Nishida ; Yoko Ogawa ; Jun Shimazaki ; Hitoshi Watanabe ; Masakazu Yamada ; Masahiko Yamaguchi
• 关键词：consensus ; definition of dry eye ; diagnosis of dry eye ; dry eye ; tear film breakup time ; tear film oriented therapy
• 刊名：The Ocular Surface
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：15
• 期：1
• 页码：65-76
• 全文大小：2626 K
• 卷排序：15

文摘

For the last 20 years, a great amount of evidence has accumulated through epidemiological studies that most of the dry eye disease encountered in daily life, especially in video display terminal (VDT) workers, involves short tear film breakup time (TFBUT) type dry eye, a category characterized by severe symptoms but minimal clinical signs other than short TFBUT. An unstable tear film also affects the visual function, possibly due to the increase of higher order aberrations. Based on the change in the understanding of the types, symptoms, and signs of dry eye disease, the Asia Dry Eye Society agreed to the following definition of dry eye: “Dry eye is a multifactorial disease characterized by unstable tear film causing a variety of symptoms and/or visual impairment, potentially accompanied by ocular surface damage.” The definition stresses instability of the tear film as well as the importance of visual impairment, highlighting an essential role for TFBUT assessment. This paper discusses the concept of Tear Film Oriented Therapy (TFOT), which evolved from the definition of dry eye, emphasizing the importance of a stable tear film.