Pertussis: A Persistent Cause of Morbidity and Mortality in Young Infants

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• 作者：Joseph B. Cantey ; MD¹ ; ^{joseph.cantey@utsouthwestern.edu" class="auth_mail} ; Pablo J. Sá ; nchez ; MD¹ ; Judy Tran ; MPH ; MT² ; Wendy Chung ; MD ; MPH³ ; Jane D. Siegel ; MD¹ ; ²
• 关键词：ACIP ; Advisory Committee on Immunization Practices ; CMC ; Children&rsquo ; s Medical Center Dallas ; Tdap ; Tetanus toxoid ; reduced diphtheria toxoid ; and acellular pertussis ; DTaP ; Diphtheria toxoid ; tetanus toxoid ; and acellular pertussis ; ICU ; Intensive care unit ; PCR ; Polymerase chain reaction
• 刊名：The Journal of Pediatrics
• 出版年：June 2014
• 年：2014
• 卷：164
• 期：6
• 页码：1489-1492.e1
• 全文大小：215 K

文摘

In 2012, a pertussis outbreak in Dallas County resulted in the deaths of 4 children (3, unvaccinated; 2, <60 days of age). Despite recommendations that include immunization of women preferably during the third trimester of pregnancy or postpartum, household contacts (“cocooning”), and infants as early as 42 days of age, challenges in pertussis prevention remain.