Mild parkinsonian features in dystonia: Literature review, mechanisms and clinical perspectives

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• 作者：Lucy Haggstrom^a ; ^{lucyhaggstrom@icloud.com} ; Paul Darveniza^a ; ^b ; ^{pdarveniza@stvincents.com.au} ; Stephen Tisch^a ; ^b ; ^{stisch@stvincents.com.au}
• 关键词：Dystonia ; Extrapyramidal features ; Parkinsonism ; Dystonia phenomenology ; Pathophysiology
• 刊名：Parkinsonism & Related Disorders
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：35
• 期：Complete
• 页码：1-7
• 全文大小：352 K
• 卷排序：35

文摘

Dopaminergic dysfunction plays a key role in idiopathic isolated dystonia. Parkinsonism is typically not considered part of the clinical spectrum of isolated dystonia. However, mild parkinsonian features can occur in idiopathic and familial isolated dystonia. Recognising parkinsonian features in dystonia may assist diagnosis and therapeutic research.