The Wag31 protein interacts with AccA3 and coordinates cell wall lipid permeability and lipophilic drug resistance in Mycobacterium smegmatis
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- 作者：Wen-xi Xu wenxixu10@fudan.edu.cn" class="auth_mail ; Lu Zhang ; zhanglu407@fudan.edu.cn" class="auth_mail ; Jun-tao Mai 349623669@qq.com" class="auth_mail ; Ru-chao Peng 08300300048@fudan.edu.cn" class="auth_mail ; En-zhuo Yang 072023005@fudan.edu.cn" class="auth_mail ; Chao Peng Chao.peng@merial.com" class="auth_mail ; Hong-hai Wang ; hhwang@fudan.edu.cn" class="auth_mail
- 关键词：Coiled-coil ; ACCase ; Ag84
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：6 June 2014
- 年：2014
- 卷：448
- 期：3
- 页码：255-260
- 全文大小：922 K
文摘
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We found that Wag31 interacts with AccA3.
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Lower expression of Wag31 results in higher lipid permeability.
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Lower expression of Wag31 results in lower resistance to lipophilic drugs.
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Overexpression of AccA3 results in lower lipid permeability.
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Overexpression of AccA3 results in higher resistance to lipophilic drugs.
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