Osteoarthritis year in review 2016: biology

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• 作者：E.N. Blaney Davidson ; ^{Esmeralda.blaneydavidson@radboudumc.nl} ; A.P.M. van Caam ; P.M. van der Kraan
• 关键词：Osteoarthritis ; Cartilage ; Inflammation ; Subchondral bone
• 刊名：Osteoarthritis and Cartilage
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：25
• 期：2
• 页码：175-180
• 全文大小：486 K
• 卷排序：25

文摘

This review highlights a selection of literature in the area of osteoarthritis biology published between the 2015 and 2016 Osteoarthritis Research Society International (OARSI) World Congress. Highlights were selected from a pubmed search covering cartilage, bone, inflammation and pain. A personal selection was made based, amongst other things, on topics presented during the 2015 conference. This covers circadian rhythm, TGF-β signaling, autophagy, SIRT6, exercise, lubricin, TLR's, pain and NGF. Furthermore, in this review we have made an effort to connect these seemingly distant topics into one scheme of connections between them, revealing a theoretical big picture underneath.