Protein tyrosine phosphatase 1B (PTP1B) and 伪-glucosidase inhibitory activities of Schisandra chinensis (Turcz.) Baill
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- 作者：Linlin Fanga ; b ; Jiaqing Caoa ; b ; Lili Duana ; b ; Yun Tangc ; Yuqing Zhaoa ; b ; zyq4885@126.com" class="auth_mail
- 关键词：Schisandra chinensis (Turcz.) Baill ; Protein tyrosine phosphatase 1B (PTP1B) and 伪-glucosidase inhibitory activities ; Anti-diabetes and obesity ; Functional food ingredient
- 刊名：Journal of Functional Foods
- 出版年：July 2014
- 年：2014
- 卷：9
- 期：Complete
- 页码：264-270
- 全文大小：461 K
文摘
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The stems of SCTZ's anti-diabetes effect and the fractions and constituents against the PTP1B and 伪-glucosidase mechanism is reported for the first time.
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Four fractions and 10 known compounds were evaluated for protein tyrosine phosphatase 1B and 伪-glucosidase inhibitory activities from Schisandra chinensis (Turcz.) Baill.
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All fractions and constituents exhibited significant inhibitory activities.
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IC50 values of compound 1 and PE fraction for PTP1B was lower than 5 渭M or 渭g/mL.
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IC50 values of EtOAc extract for 伪-glucosidase was lower than 2 渭g/mL.
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