Bokhman Redux: Endometrial cancer “types” in the 21st century

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• 作者：Adrian A. Suarez^a ; ^{Adrian.Suarez@osumc.edu} ; Ashley S. Felix^b ; David E. Cohn^c
• 关键词：Endometrial cancer ; Endometrial carcinoma ; Metabolic syndrome ; Obesity ; Cancer risk ; Risk factor
• 刊名：Gynecologic Oncology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：144
• 期：2
• 页码：243-249
• 全文大小：1797 K
• 卷排序：144

文摘

A landmark 1983 Gynecologic Oncology paper defined two types of endometrial cancer. Type I was associated with metabolic syndrome, low stage and low grade tumors. Type II was associated with high grade and clinically aggressive tumors. This view has contributed greatly to endometrial cancer understanding and teaching. Recent molecular, epidemiologic and pathologic advances challenge a dualistic view.