Efficacy of scaling and root planing with and without adjunct antimicrobial photodynamic therapy on the expression of cytokines in the gingival crevicular fluid of patients with periodontitis: A systematic review

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• 作者：Sergio Varela Kellesarian^a ; ^{sergio_kellesarian@urmc.rochester.edu} ; Vanessa Ros Malignaggi^b ; Tariq Abduljabbar^c ; Fahim Vohra^c ; Hans Malmstrom^a ; Georgios E. Romanos^d ; ^e ; Fawad Javed^a
• 关键词：Cytokines ; Periodontal debridement ; Periodontal diseases ; Periodontitis ; Photochemotherapy
• 刊名：Photodiagnosis and Photodynamic Therapy
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：Complete
• 页码：76-84
• 全文大小：561 K
• 卷排序：16

文摘

Six clinical trials were included in the present systematic review. Two studies reported lower pro-inflammatory (IL-1β, TGF-β1 and MMP-8) cytokines among individuals that underwent SRP with adjunct aPDT compared with SRP alone. Three studies reported reduction in selective cytokines in the GCF following SRP with adjunct aPDT compared with SRP alone. In one study SRP with adjunct aPDT failed to reduce GCF IL-1β at follow-up.