BTLA-expressing CD11c antigen presenting cells in patients with active tuberculosis exhibit low capacity to stimulate T cell proliferation

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• 作者：Wan-Dang Wang^a ; ^d ; ¹ ; Yu-Chi Gao^a ; ^c ; ¹ ; Yuan-Bin Lu^a ; ^c ; ¹ ; Jun-Ai Zhang^a ; ^c ; Gan-Bin Liu^b ; Bin Kong^a ; ^c ; Wen-Yu Xiang^a ; ^c ; You-Chao Dai^a ; ^c ; Shi-Yan Yu^a ; ^c ; Yan Jia^a ; ^c ; Xiao-Xia Fu^a ; Lai-Long Yi^b ; Bin-Ying Zheng^a ; Zheng W. Chen^d ; Jixin Zhong^e ; Jun-Fa Xu^a ; ^c ; ^{imxujunfa@163.com} ; ^{xujunfa@gdmu.edu.cn}
• 关键词：B and T lymphocyte attenuator ; CD11c APCs ; Stimulatory capacity ; Antigen uptake ; HLA-DR ; HLA-I(A ; B ; C) ; CD86 ; IL-6
• 刊名：Cellular Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：311
• 期：Complete
• 页码：28-35
• 全文大小：1311 K
• 卷排序：311

文摘

BTLA associated with the attenuated stimulatory capacity on T cells proliferation. Stimulatory capacity of BTLA-expressing CD11c APCs to T cell proliferation was impaired, which may be associated with low expression of HLA-DR and less IL-6 secretion.