Magnetic compression anastomosis for enteroenterostomy under peritonitis conditions in dogs

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• 作者：Hongke Zhang ; MD ; PhD^a ; ¹ ; Kai Tan ; MD^b ; ¹ ; Chao Fan ; MD^b ; Jingwei Du ; MD^c ; Jiangbin Li ; MD^b ; Tao Yang ; MD^b ; Yi Lv ; MD ; PhD^a ; Xilin Du ; MD ; PhD^b ; ^{dxlin0705@163.com}
• 关键词：Peritonitis ; Enteroenterostomy ; Magnetic compression anastomosis ; Hand-sewn anastomosis ; Stapled anastomosis
• 刊名：Journal of Surgical Research
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：60-67
• 全文大小：4209 K
• 卷排序：208

文摘

The risk of complications and mortality are high after enteroenterostomy in severe peritonitic conditions. Magnetic compression anastomosis (MCA) is a sutureless technique of high efficacy and safety. The purpose of this study was to compare the efficacy of MCA for enteroenterostomy with stapled and hand-sewn techniques under peritonitic conditions.MethodsThe peritonitic conditions were created by puncturing the colon with a circular blade in 27 mongrel dogs. Eight hours later, the peritoneal cavity was washed with warm, sterilized normal saline solution. The animals were then randomly divided into three groups and underwent colonic anastomosis with MCA, stapled, or hand-sewn techniques, respectively. Animals were euthanized at 1, 2, and 4 w after the operation; anastomoses were compared on the basis of gross appearance and histology.ResultsAll magnetic devices formed patent anastomoses without a leak. However, one stapled anastomosis and three hand-sewn anastomoses resulted in leaks. The anastomosis time was significantly less in the MCA group than that of the other two groups (P < 0.05). All magnetic devices were expelled naturally. The pathologic observation showed that the healing of anastomoses for MCA was smoother than that of the other two groups.ConclusionMCA is a feasible, safe, and effective alternative for enteroenterostomy under peritonitic conditions in the canine model.