The fatty acid mixture tested in this study (high ω-9:ω-6 ratio and low ω-6:ω-3 ratio) effectively reduced TNF-α levels post tooth extraction in rats. The fatty acid mixture tested in this study (high ω-9:ω-6 ratio and low ω-6:ω-3 ratio) effectively reduced myeloperoxidase levels post tooth extraction in rats. Clinically the fatty acid mixture tested in this study (high ω-9:ω-6 ratio and low ω-6:ω-3 ratio) effectively reduced masseter edema post tooth extraction in rats. Histologically the fatty acid mixture tested in this study (high ω-9:ω-6 ratio and low ω-6:ω-3 ratio) effectively reduced osteoclast numbers at the site of dental extraction in rats.