miR-144-3p as a novel plasma diagnostic biomarker for clear cell renal cell carcinoma

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• 作者：Ning Lou ; Ph.D.^a ; An-Ming Ruan ; M.S.^a ; Bin Qiu ; M.S.^a ; Lin Bao ; M.S.^a ; Yu-Chen Xu ; M.D.^a ; Yan Zhao ; Ph.D.^b ; Ru-Lin Sun ; Ph.D.^b ; San-Tao Zhang ; M.S.^b ; Guang-Hua Xu ; Ph.D.^a ; Hai-Long Ruan ; Ph.D.^a ; Chang-Fei Yuan ; M.S.^a ; Wei-Wei Han ; Ph.D.^a ; Hang-Chuan Shi ; Ph.D.^a ; Hong-Mei Yang ; Ph.D.^b ; Xiao-Ping Zhang ; M.D. ; Ph.D.^a ; ^{xzhang@hust.edu.cn}
• 关键词：miR-144-3p ; Clear cell renal cell carcinoma ; Plasma ; Biomarker
• 刊名：Urologic Oncology: Seminars and Original Investigations
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：35
• 期：1
• 页码：36.e7-36.e14
• 全文大小：1918 K
• 卷排序：35

文摘

Plasma miR-144-3p acted excellently in discriminating ccRCC from healthy controls. Plasma miR-144-3p could aid in the differential diagnosis for ccRCC from AML well. Plasma miR-144-3p decreased significantly after nephrectomy in ccRCC. Plasma and tissue miR-144-3p levels were significantly increased in ccRCC. Plasma and tissue miR-144-3p levels in ccRCC were related to advanced pT stage.