Osteoclastogenic capacity of peripheral blood mononuclear cells is not different between women with and without osteoporosis

详细信息    查看全文

• 作者：W.N.H. Koek ; B.C.J. van der Eerden ; ^{b.vandereerden@erasmusmc.nl} ; R.D.A.M. Alves ; M. van Driel ; M. Schreuders-Koedam ; M.C. Zillikens ; J.P.T.M. van Leeuwen
• 关键词：Osteoclasts ; Peripheral blood mononuclear cells ; Deoxypyridinoline ; Osteoporosis ; Fractures
• 刊名：Bone
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：108-114
• 全文大小：636 K
• 卷排序：95

文摘

The osteoclastogenic differentiation capacity of PBMCs from postmenopausal women with and without osteoporosis is similar Osteoclast formation ability of PBMCs in vitro correlates well with with the mean resorbed bone area on bone slices Postmenopausal women with osteoporosis and low DPD levels have lower osteoclast potential and resorption capacity in vitro