Predictors of mortality in bloodstream infections caused by multidrug-resistant gram-negative bacteria: 4 years of collection

详细信息    查看全文

• 作者：Weiwei Wang ; MM^a ; Ting Jiang ; MM^a ; Weihong Zhang ; MD^b ; Chunyu Li ; MM^a ; Jun Chen ; MM^a ; Dandan Xiang ; MPH^c ; Kejiang Cao ; MD^d ; Lian-Wen Qi ; PhD^e ; Ping Li ; PhD^e ; Wei Zhu ; MD^f ; Wensen Chen ; MPH^b ; ^{metrischen@126.com} ; Yan Chen ; MD^a ; ^g ; ^{chenyandoc@163.com}
• 关键词：Carbapenem-resistant ; Gram-negative bacilli ; Risk factor ; Therapy
• 刊名：American Journal of Infection Control
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：45
• 期：1
• 页码：59-64
• 全文大小：366 K
• 卷排序：45

文摘

MDR-GNB strains and antimicrobial regimens were not the major risk factors for mortality. The inadequate initial antibiotic, invasive procedures, high APACHE II scores, hospitalization of ICU, and comorbidities were the important factors responsible for mortality. Although there was no difference between combination therapy and monotherapy in mortality, combined treatment may be more effective than monotherapy for patients of ICU, Charlson comorbidity score < 4 or inadequate initial antimicrobial treatment.