Quality of life after Uphold™ Vaginal Support System surgery for apical pelvic organ prolapse—A prospective multicenter study

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• 作者：Pä ; ivi Rahkola-Soisalo^a ; ^{paivi.rahkola-soisalo@hus.fi} ; Daniel Altman^b ; ^c ; Christian Falconer^c ; Edward Morcos^c ; Martin Rudnicki^d ; Tomi S. Mikkola^a ; ^e
• 关键词：Quality of life ; Pelvic organ prolapse ; Cystocele ; Uterine prolapse ; Transvaginal mesh
• 刊名：European Journal of Obstetrics & Gynecology and Reproductive Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：86-90
• 全文大小：294 K
• 卷排序：208

文摘

To study the effects on quality of life in women operated for apical pelvic organ prolapse using the Vaginal Uphold™ System.Study designIn this prospective cohort study, women (n = 207) with symptomatic apical prolapse, with or without cystocele, were operated using the Uphold™ Vaginal Support System. Follow-up for quality of life was performed at 12 months after surgery, and assessed by the PFDI-20, and PFIQ-7, and sexual function by the PISQ-12. We used odds ratios (ORs) with 95% confidence intervals (CIs) for outcome association analyses using logistic regression.ResultsAt one-year follow-up majority of women experienced an overall postoperative improvement in quality of life (p < 0.001). One year after surgery Uphold™ operation alone increased the risk for prolapse related bother as compared to Uphold™ combined with anterior colporraphy (POP-IQ-7; OR 2.1; 95% CI 1.01–4.3). The frequency of dyspareunia decreased postoperatively (p = 0.004), however, after one-year, overall sexual function deteriorated significantly (p < 0.001). The worsening in sexual function scores was mainly attributed to the partner related domain, whereas the behavioral-emotive and physical domains showed no significant changes.ConclusionApical prolapse repair using Uphold™ improved quality of life among our patients but worsened overall sexual function postoperatively.