Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography

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• 作者：Mihá ; ly Ká ; rolyi^a ; ¹ ; ^{mihaly.karolyi@cirg.hu} ; Bá ; lint Szilveszter^a ; ¹ ; ^{szilveszter.balint@gmail.com} ; Má ; rton Kolossvá ; ry^a ; ^{martonandko@gmail.com} ; Richard A.P Takx^b ; ^{richard.takx@gmail.com} ; Csilla Celeng^a ; ^{celengcsilla@gmail.com} ; Andrea Bartykowszki^a ; ^{bartyandi@gmail.com} ; Á ; dá ; m L. Jermendy^a ; ^{adam.jermendy@gmail.com} ; Alexisz Panajotu^a ; ^{panajotualexisz@gmail.com} ; Jú ; lia Kará ; dy^a ; ^{karadyjulia@gmail.com} ; Rolf Raaijmakers^c ; ^{rolf.raaijmakers@philips.com} ; Walter Giepmans^c ; ^{walter.giepmans@philips.com} ; Bé ; la Merkely^a ; ¹ ; ^{merkely.bela@gmail.com} ; Pá ; l Maurovich-Horvat^a ; ¹ ; ^{p.maurovich.horvat@mail.harvard.edu} ; ^{maurovich.horvat@gmail.com}
• 关键词：CTA ; computed tomography angiography ; CX ; circumflex artery ; FBP ; filtered back projection ; HIR ; hybrid iterative reconstruction ; HU ; Hounsfield units ; IMR ; iterative model reconstruction ; LAD ; left anterior descending artery ; RCA ; right coronary artery ; SCCT ; Society of Cardiovascular Computed Tomography
• 刊名：European Journal of Radiology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：87
• 期：Complete
• 页码：83-89
• 全文大小：1232 K
• 卷排序：87

文摘

To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA).MethodsRaw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software.ResultsOverall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p < 0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5&ndash;59.9], 20.3 [16.2&ndash;25.9] and 14.0 [11.2&ndash;17.7], respectively, all p < 0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3&ndash;168.4], 138.7 [90.6&ndash;191.7], 147.0 [100.7&ndash;183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1&ndash;144.6], 110.2 [63.8&ndash;166.6], 115.9 [81.7&ndash;164.2], respectively, p < 0.05 all). High-attenuation non-calcified volumes (90&ndash;129 HU) yielded similar values with FBP and HIR (p = 0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30&ndash;89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p = 0.22 and p = 0.67, respectively).ConclusionsIMR improves image quality of coronary CTA and decreases calcified plaque volumes.