A combination of Korean mistletoe extract and resistance exercise retarded the decline in muscle mass and strength in the elderly: A randomized controlled trial

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• 作者：Nam Ju Lim^a ; ¹ ; Jun Ho Shin^b ; ¹ ; Hye Jin Kim^c ; Yeni Lim^a ; Ji Yeon Kim^d ; Won Jun Lee^c ; Soo Jeong Han^b ; ^{ocrystal@ewha.ac.kr} ; Oran Kwon^a ; ^{orank@ewha.ac.kr}
• 关键词：KME ; aqueous extract of Korean mistletoe ; EMG ; electromyography ; FoxO1 ; forkhead box protein O1 ; GAPDH ; glyceraldehyde 3-phosphate dehydrogenase ; GSK3 ; glycogen synthase kinase 3 ; IGF ; insulin growth factor ; IR ; insulin receptor ; IRS1 ; insulin receptor substrate 1 ; IGF1R ; insulin-like growth factor 1 receptor ; LS mean ; least-squares mean ; mTOR ; mechanistic target of rapamycin ; MyoD ; myogenic determination ; p70S6K ; p70 ribosomal protein S6 kinase ; PP ; per protocol ; PTEN ; phosphatase and tensin ho
• 刊名：Experimental Gerontology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：87
• 期：part_PA
• 页码：48-56
• 全文大小：691 K
• 卷排序：87

文摘

We tested impact of KME on declines in muscle mass and strength in the elderly. Muscle mass, knee strength, and balance ability improved with KME supplementation. IGF1R, atrogin-1, and myogenin were involved in the modulating effect of KME.