Cyclic loading of human articular cartilage: The transition from compaction to fatigue

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• 作者：Jonathan T. Kaplan^a ; ^b ; Corey P. Neu^c ; Hicham Drissi^d ; Nancy C. Emery^e ; David M. Pierce^a ; ^{dmpierce@engr.uconn.edu}
• 关键词：Articular cartilage ; Osteoarthritis ; Unconfined compression ; Fatigue ; Creep
• 刊名：Journal of the Mechanical Behavior of Biomedical Materials
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：65
• 期：Complete
• 页码：734-742
• 全文大小：1517 K
• 卷排序：65

文摘

Performed cyclic compression with periodic tests of cartilages' functional responses. Load frequency significantly affected cartilages' time to equilibrium. Force–frequency interaction had significant effect on time to equilibrium, thickness. Increased load cycles significantly affected cartilages' stiffness and thickness. Multi-modal images provided insight to microstructural alterations in P'G and collagen.