Network Dynamics Mediate Circadian Clock Plasticity

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• 作者：Abdelhalim Azzi¹ ; ⁶ ; Jennifer A. Evans² ; ⁶ ; ^{jennifer.evans@marquette.edu} ; Tanya Leise³ ; Jihwan Myung⁴ ; Toru Takumi⁴ ; Alec J. Davidson⁵ ; ^{adavidson@msm.edu} ; Steven A. Brown¹ ; ⁷ ; ^{steven.brown@pharma.uzh.ch}
• 关键词：whole-cell ; patch clamp ; in vivo ; thalamus ; subcortical ; automation ; autopatcher
• 刊名：Neuron
• 出版年：2017
• 出版时间：18 January 2017
• 年：2017
• 卷：93
• 期：2
• 页码：441-450
• 全文大小：3239 K
• 卷排序：93

文摘

Circadian phasing of SCN subregions is stably altered by light:dark cycle length Changes in DNA methylation are region specific and necessary for network changes SCN network reorganization requires GABAergic signaling Interruption of neural communication abolishes circadian aftereffects of altered light