Dopamine D1 receptor agonist treatment attenuates extinction of morphine conditioned place preference while increasing dendritic complexity in the nucleus accumbens core

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• 作者：Kendra L. Kobrin^a ; ^c ; ^{kendrak@bu.edu} ; Danielle T. Arena^a ; ^{DanielleTArena@gmail.com} ; Stephen C. Heinrichs^a ; ^{Stephen.Heinrichs@va.gov} ; Olivia H. Nguyen^a ; ^{ohnguyen@bu.edu} ; Gary B. Kaplan^b ; ^c ; ^d ; ^{Gary.Kaplan@va.gov}
• 关键词：Morphine ; Opioid ; Nucleus accumbens ; Dopamine ; Dendrite ; Reward ; Extinction
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：30 March 2017
• 年：2017
• 卷：322
• 期：part_PA
• 页码：18-28
• 全文大小：1889 K
• 卷排序：322

文摘

D1R agonist given after extinction training attenuates extinction of morphine CPP. D1R agonist given after extinction increases dendritic complexity in accumbens core. D1R agonist effect on accumbal dendritic morphology depends on previous conditioning.