Nucleoplasmic bridges as a biomarker of DNA damage exposed to radon

详细信息    查看全文

• 作者：C. Meenakshi ; ^{c.meenakshi02@gmail.com} ; K. Sivasubramanian ; B. Venkatraman
• 关键词：Micronucleus ; Nucleoplasmic bridges ; Radon ; DNA damage ; Smokers
• 刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：814
• 期：Complete
• 页码：22-28
• 全文大小：1000 K
• 卷排序：814

文摘

CBMN assay has been proved effective in the study of chromosome damage induced by radon. First of its kind to investigate Nucleoplasmic bridges as a biomarker of early DNA damage induced by radon. Frequencies of Mn in smoker cells are increased by a factor of four. The study indicates the usefulness of micronucleus analysis as a biological exposure index for individuals risk assessment.