A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures
A systems toxicology approach was applied to comprehensively assess the biological impact of a heated tobacco aerosol and cigarette smoke Series of experimental repetitions were conducted to increase robustness of the assessment Heated tobacco aerosol elicited less biological impact than cigarette smoke at similar nicotine concentration(s)