Histone Methyltransferase aflrmtA gene is involved in the morphogenesis, mycotoxin biosynthesis, and pathogenicity of Aspergillus flavus

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• 作者：Yu Li ; Yizi He ; Xing Li ; Opemipo Esther Fasoyin ; Yule Hu ; Yaju Liu ; Jun Yuan ; Zhenhong Zhuang ; ^{xzhzhenhong@163.com} ; Shihua Wang ; ^{wshyyl@sina.com}
• 关键词：aflrmtA gene ; Histone methyltransferase ; A. flavus ; AFB1 ; Pathogenicity
• 刊名：Toxicon
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：127
• 期：Complete
• 页码：112-121
• 全文大小：3210 K
• 卷排序：127

文摘

Gene aflrmtA down-regulates conidiation through brlA and abaA genes, and increases sclerotia formation by nsdC and nsdD genes. aflrmtA gene up-regulates AFB1 biosynthesis in PDA and PDB media by aflR, aflC and aflK genes. aflrmtA involves inflavus response to plasma membrane lesion, osmotic, and H2O2-induced oxidative stresses. In A. flavus, aflrmtA represses conidiation and up-regulates the AFB1 biosynthesis on peanut and corn seeds. aflrmtA up-regulates the activities of protease and lipase, but down-regulates the activity of amylase.