• 作者：M. José ; Bosque Ló ; pez^a ; ^{mjbosque@hsd.es} ; Carmen Garrido Durá ; n^a ; Daniel Ginard Vicens^a ; M. Antonia Munar Vila^b ; Margalida Vanrell Garau^a ; Zoe Mariñ ; o Mé ; ndez^a ; Jaime Gayà ; Cantallops^a
• 关键词：Mesalazina ; Enfermedad inflamatoria intestinal ; Nefritis intersticial ; Monitorizació ; n de la funció ; n renal
• 刊名：Gastroenterolog¨ªa y Hepatolog¨ªa
• 出版年：2009
• 出版时间：January 2009
• 年：2009
• 卷：32
• 期：1
• 页码：29-31
• 全文大小：369 K

We report a new case of chronic interstitial nephritis in a patient with ulcerative colitis diagnosed in 2002 who was originally treated with 5-ASA. Three years later deterioration of renal function was apparent with an increase in serum creatinine, which was normal before treatment. Withdrawal of 5-ASA led to partial improvement of renal function. In patients with a delayed diagnosis of kidney damage, recovery of renal function is incomplete and, in some cases, the patient even requires some form of renal replacement therapy. We stress the importance of monitoring renal function in patients diagnosed with inflammatory bowel disease treated with this drug.