• 作者：R.M. Gó ; mez Punter¹ ; ^{rosamar_gp@hotmail.com} ; R.M. Giró ; n¹ ; J.A. Garcí ; a Romero de Tejada¹ ; G. Segrelles¹ ; P. Caballero² ; P. Cano¹ ; C. Martí ; n-Carbajo¹
• 关键词：Inmunodeficiencia com&uacute ; n variable ; CVID ; Inmunoglobulinas ; Infecciones sinopulmonares
• 刊名：Revista de Patolog¨ªa Respiratoria
• 出版年：2009
• 出版时间：October-December 2009
• 年：2009
• 卷：12
• 期：4
• 页码：168-170
• 全文大小：61 K

Common variable immunodeficiency (CVID) is the primary immunodeficiency frequently found in the clinical practice. Clinically, it is defined as the presence of recurrent infections and a reduction in IgG serum (at least 2 standard deviations before the reference values for the subject's age) and at least another one of the Ig (IgA or IgM) and a reduction or absence of the production of antibody titers protectors for polysaccharide vaccines and protein antigens. The clinical manifestations of these patients are multiple sinopulmonary infections, systemic bacterial infections and gastrointestinal complications, the sinopulmonary infections being the clinical manifestations found most. The principal basis of the CVID treatment is the immunoglobulin replacement treatment, together with antibiotics for the infections and adequate treatment of the non-infectious complications.