Facile Strategy to Well-Defined Water-Soluble Boronic Acid (Co)polymers

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• 作者：Jennifer N. Cambre ; Debashish Roy ; Sudershan R. Gondi ; Brent S. Sumerlin
• 刊名：Journal of the American Chemical Society
• 出版年：2007
• 出版时间：August 29, 2007
• 年：2007
• 卷：129
• 期：34
• 页码：10348 - 10349
• 全文大小：94K
• 年卷期：v.129,no.34(August 29, 2007)
• ISSN：1520-5126

文摘

A facile route to well-defined boronic acid (co)polymers from stable and easily manipulated boronic ester monomers is presented. The polymerization of 4-pinacolatoborylstyrene by reversible addition-fragmentation chain transfer (RAFT) yielded polymeric boronic acid precursors. Selection of stoichiometry allowed tuning of polymerization kinetics and targeting specific molecular weights in the range of M_n = 17000-32000 g/mol. The resulting low polydispersity poly(4-pinacolatoborylstyrene) homopolymers were employed as macro-chain transfer agents for block copolymerization with N,N-dimethylacrylamide to yield amphiphilic block copolymers that formed micelles in aqueous media. The pinacol ester derivatized (co)polymers were easily deprotected by a mild and convenient strategy to yield free boronic acid polymers