Reversibly Caged Glutamate: A Photochromic Agonist of Ionotropic Glutamate Receptors

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• 作者：Matthew Volgraf ; Pau Gorostiza ; Stephanie Szobota ; Max R. Helix ; Ehud Y. Isacoff ; Dirk Trauner
• 刊名：Journal of the American Chemical Society
• 出版年：2007
• 出版时间：January 17, 2007
• 年：2007
• 卷：129
• 期：2
• 页码：260 - 261
• 全文大小：72K
• 年卷期：v.129,no.2(January 17, 2007)
• ISSN：1520-5126

文摘

The design, synthesis, and biological evaluation of a photochromic glutamate analogue is described. The molecule functions as a reversibly caged neurotransmitter and can be used to influence neural activity with light.