Antitubercular Dihydroagarofuranoid Sesquiterpenes from the Roots of Microtropis fokienensis

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• 作者：Jih-Jung Chen ; Tsung-Hsien Chou ; Chien-Fang Peng ; Ih-Sheng Chen ; Sheng-Zehn Yang
• 刊名：Journal of Natural Products
• 出版年：2007
• 出版时间：February 2007
• 年：2007
• 卷：70
• 期：2
• 页码：202 - 205
• 全文大小：92K
• 年卷期：v.70,no.2(February 2007)
• ISSN：1520-6025

文摘

Four new dihydroagarofuranoid sesquiterpenes (1-4) and a new hydroxybenzylsalicylaldehyde, forkienin (5), togetherwith nine known compounds have been isolated from the roots of Microtropis fokienensis. The structures of the newcompounds were determined through analyses of physical data. Compounds 3, 4, 7, and 8 exhibited potent antitubercularactivities (MICs 26.0 M) against Mycobacterium tuberculosis 90-221387 in vitro.