Simple Chiral Chain Dienes as Ligands for Rh(I)-Catalyzed Conjugated Additions

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• 作者：Xichao Hu ; Minyang Zhuang ; Ziping Cao ; Haifeng Du
• 刊名：Organic Letters
• 出版年：2009
• 出版时间：October 15, 2009
• 年：2009
• 卷：11
• 期：20
• 页码：4744-4747
• 全文大小：200K
• 年卷期：v.11,no.20(October 15, 2009)
• ISSN：1523-7052

文摘

This paper describes that a simple and readily available chain diene (3R,4R)-hexa-1,5-diene-3,4-diol (L1) was successfully utilized as a novel steering ligand for Rh(I)-catalyzed asymmetric conjugated additions. Encouraging yields and ee’s have been achieved, which may provide a new and practical direction for designing chiral diene ligands in the future.